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The Glaser coupling is a type of coupling reaction. It is by far the oldest acetylenic coupling and is based on cuprous salts like copper(I) chloride or copper(I) bromide and an additional oxidant like oxygen. The base in its original scope is ammonia. The solvent is water or an alcohol. The reaction was first reported by Carl Andreas Glaser in 1869. 800px In 1882 Adolf von Baeyer used the method to synthesise indigo dye from cinnamic acid. Baeyer indigo synthesis Shortly afterwards, Baeyer reported a different route to indigo, now known as the Baeyer–Drewson indigo synthesis. ==See Also== * Cadiot–Chodkiewicz coupling - Another alkyne coupling reaction catalysed by copper (I). * Sonogashira coupling - Pd/Cu catalysed coupling of an alkyne and an aryl or vinyl halide * Castro–Stephens coupling - A cross-coupling reaction between a copper(I) acetylide and an aryl halide 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Glaser coupling」の詳細全文を読む スポンサード リンク
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